Combine the onion powder, garlic powder, smoked paprika, and dried oregano in a small bowl. Stir until the seasonings are evenly distributed.
Coat a large pan lightly with cooking spray and place it over medium-high heat. Add the lean ground beef, then season with salt and ground black pepper according to taste.
Cook for approximately 5 minutes, stirring from time to time, until the beef has browned and no pink remains.
Stir the coarsely chopped pepperoni into the cooked beef, followed by the prepared seasoning mixture.
Continue cooking for another 2 minutes, stirring occasionally, until the pepperoni develops a light golden color and becomes aromatic.
Add the crushed tomatoes, tomato paste, and chopped flat-leaf parsley to the beef and pepperoni mixture. Stir thoroughly so all ingredients are evenly incorporated.
Bring the mixture to a gentle simmer and cook for 2–3 minutes, allowing excess moisture to evaporate and the filling to thicken. Remove the pan from the heat once the mixture is rich and no longer watery.
Arrange the six wraps on a flat work surface. Divide the prepared beef, pepperoni, and tomato filling evenly among them.
Distribute the shredded low-fat mozzarella over the filling, then add a small drizzle of your preferred sauce if desired.
Fold and roll each wrap firmly into a burrito-style shape, keeping the filling securely enclosed.
Arrange the filled wraps seam-side down on a baking tray or place them in an air fryer basket. Lightly coat their surfaces with cooking spray. Additional chopped flat-leaf parsley may be scattered over the top if desired.
For the oven method, bake in a preheated oven at 200°C (400°F) for 8–10 minutes.
For the air fryer method, cook at 180°C (350°F) for 8–10 minutes.
The pizza rolls are ready when the exterior is crisp and lightly golden and the mozzarella inside has melted.
Allow them to cool for several minutes before slicing or serving.