Discover how to elevate a classic comfort food with this Mediterranean Grilled Cheese Sandwich packed with spinach, feta, and mozzarella.

The result is a crispy, savory, and satisfying bite.

This gourmet grilled cheese comes together in just 15 minutes, making it a perfect choice for a flavorful and nutritious lunch or light dinner.

Key Ingredients in Mediterranean Grilled Cheese Sandwich

Olive oil – Adds a rich, fruity base for sautéing the garlic and spinach, enhancing the sandwich’s Mediterranean flair.
Garlic – Offers a bold, aromatic foundation that deepens the flavor of the spinach filling.
Frozen chopped spinach – Convenient and nutritious, it adds a tender texture and a dose of greens.
Mozzarella cheese – Melts beautifully to create a gooey, creamy base that balances the sharpness of feta.
Feta cheese – Brings a tangy, salty kick that defines the Mediterranean profile.
Crushed red pepper – A touch of heat elevates the savory flavors without overwhelming them.
Butter – Ensures a golden, crispy exterior that contrasts perfectly with the gooey interior.
Bread – The canvas for all the goodness; use a sturdy slice that crisps well while holding up to the filling.

How to Assemble This Mediterranean Grilled Cheese Sandwich

This sandwich is all about layering vibrant ingredients and toasting them to golden perfection.

Start by sautéing garlic and spinach until the moisture cooks off. Layer mozzarella, feta, and the spinach mixture between slices of buttered bread, then grill until crisp and melty. Serve warm and enjoy the perfect blend of creamy, savory, and crunchy.

Tips to Perfect Your Mediterranean Grilled Cheese Sandwich

To prevent a soggy sandwich, make sure the spinach is well-sautéed until most of the liquid evaporates. Use thick-cut bread that crisps well and holds the filling securely. For added flavor, try brushing the outside of the bread with a garlic herb butter or sprinkling sesame seeds on the crust before grilling.

How to Store Leftovers of Mediterranean Grilled Cheese Sandwich

For best results, store leftover sandwiches wrapped in foil or an airtight container in the refrigerator for up to 2 days. Reheat in a skillet or toaster oven to restore crispness—avoid microwaving, as it may make the bread soggy. Freezing is not recommended due to the moisture content in the spinach and cheese.

Frequently Asked Questions

Can I use fresh spinach instead of frozen?
Yes, just sauté it down until wilted. You may need more volume to match the yield of frozen spinach.

What type of bread works best?
Use a sturdy variety like sourdough or whole grain to hold up to the moist filling and achieve a crispy crust.

Can I make it dairy-free?
Yes, use plant-based mozzarella and feta alternatives and a vegan butter substitute.

Is this sandwich kid-friendly?
Absolutely! You can reduce or omit the crushed red pepper for a milder version.

Mediterranean Grilled Cheese Sandwich

Elevate your lunchtime routine with this gourmet Mediterranean Grilled Cheese Sandwich. Brimming with spinach, creamy feta, and melted mozzarella, this savory creation offers a Mediterranean twist on a classic comfort food staple.
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Prep Time: 5 minutes
Cook Time: 10 minutes
Total Time: 15 minutes

Ingredients

  • 1 oz. feta cheese crumbled
  • 1 pinch crushed red pepper flakes
  • 1/2 Tbsp olive oil
  • 1 pinch salt and pepper
  • 4 slices sandwich bread
  • 1 clove garlic finely minced
  • 1 cup shredded mozzarella cheese
  • 2 Tbsp butter softened
  • 1/4 lb. frozen chopped spinach

Instructions

  • Warm the olive oil in a skillet over medium heat. Stir in the minced garlic and sauté for one minute, allowing it to become aromatic. Add the frozen spinach straight from the freezer, along with a pinch of salt and pepper, and continue cooking until the excess moisture has evaporated.
  • Generously butter one side of each slice of bread. Place them buttered-side down to begin assembling the sandwiches.
  • Layer half of the shredded mozzarella evenly onto two slices. Sprinkle crumbled feta on top of the mozzarella.
  • Spoon the cooked spinach mixture over the cheese layer, then add the remaining mozzarella and a light pinch of crushed red pepper flakes.
  • Complete the sandwiches with the remaining bread slices, buttered-side facing outwards.
  • Preheat a large skillet over medium-low heat. Once hot, place the sandwiches in the skillet and grill until each side is golden and crisp, and the cheese has melted to a gooey texture.
  • Slice each sandwich in half and serve warm.
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